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Items: 3

1.

Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase over-expressing mice defines an immune-associated gene signature linked to tamoxifen resistance

(Submitter supplied) To investigate response or resistance to endocrine therapy, mice with targeted over-expression of Esr1 or CYP19A1 to mammary epithelial cells were employed, representing two direct pathophysiological interventions in estrogen pathway signaling. Both Esr1 and CYP19A1 over-expressing mice responded to letrozole with reduced HAN prevalence and decreased mammary epithelial cell proliferation. CYP19A1 over-expressing mice were tamoxifen-sensitive but Esr1 over-expressing mice were tamoxifen-resistant. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
17 Samples
Download data: TXT
Series
Accession:
GSE63857
ID:
200063857

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8358 Series
188884 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

3.

Paired-end_AROM_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558523
ID:
301558523

SRA Run Selector

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db=gds|term=GSM1558523[Accession]|query=1|qty=2|blobid=MCID_67599e6d123afd30a73a2acf|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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