GSM1516039[Accession] - GEO DataSets

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Items: 4

Select item 2000620061.

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL19197
144 Samples

Download data: TXT

Series

Accession:: GSE62006

ID:: 200062006

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000618712.

Development of gene expression signatures with lncRNAs for coculture of CD34+ T-cells with an OP9-DLL1 feeder layer

(Submitter supplied) Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T-cell acute lymphoblastic leukemias, supporting an essential driver role for this gene in T-cell acute lymphoblastic leukemia oncogenesis. more...