GEO DataSets

(Submitter supplied) ErbB receptor ligands, epidermal growth factor (EGF) and heregulin (HRG), induce dose-dependent transient and sustained intracellular signaling, proliferation and differentiation of MCF-7 breast cancer cells, respectively. In an effort to delineate the ligand-specific cell determination mechanism, we investigated time-course gene expressions induced by EGF and HRG that induce distinct cellular phenotypes in MCF-7 cells. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2626

Platform:

GPL571

57 Samples

Download data: CEL, EXP

Analysis of MCF-7 breast cancer cells treated with various doses of epidermal growth factor (EGF) or heregulin (HRG) for up to 90 minutes. EGF and HRG induce distinct kinase kinetics and phenotypes of MCF-7 cells. Results provide insight into the linkage between signaling dynamics and cell fate.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 agent, 5 dose, 8 time sets

Platform:

GPL571

Series:

GSE6462

57 Samples

Download data: CEL, EXP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...

Organism:

Homo sapiens

84 DataSets

641 Series

12 Related Platforms

24467 Samples

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