GEO DataSets

(Submitter supplied) Understanding preimplantation development is important both for basic reproductive biology and for practical applications including regenerative medicine and livestock breeding. Global expression profiles revealed and characterized the distinctive patterns of maternal RNA degradation and zygotic gene activation, including two major transient waves of de novo transcription. The first wave corresponds to zygotic genome activation (ZGA); the second wave, named mid-preimplantation gene activation (MGA), precedes the dynamic morphological and functional changes from the morula to blastocyst stage. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS578 GDS579

Platform:

GPL870

64 Samples

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Dynamics of global gene expression changes during preimplantation development. Unfertilized eggs, fertilized egg, 2-cell embryos, 4-cell embryos, 8-cell embryos, morulae and blastocysts examined.

Organism:

Mus musculus

Type:

Expression profiling by array, log ratio, 7 development stage sets

Platform:

GPL870

Series:

GSE936

28 Samples

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(Submitter supplied) NIA Mouse 22K Microarray v1.0 contains 21,939 60-mer oligonucleotides representing sequences derived from the NIA/NIH early mouse embryo cDNA clone set. The annotation information is based on the NIA Mouse Gene Index 4.0 http://lgsun.grc.nia.nih.gov/geneindex4, which combines genome assembly sequences from public databases (RefSeq, Ensembl, Riken), and the NIA collection of public EST libraries derived from stem cells and early stage of mouse embryos, along with human-curated genetic databases to form structure models of over 40,000 genetic loci4. more...

Organism:

Mus musculus

3 DataSets

8 Series

160 Samples

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