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Items: 4

1.

Gene expression profiling: breast cancer formation in WAP-SVT/t transgenic animals

(Submitter supplied) Microarray studies revealed that as a first hit, SV40 T/t-antigen causes deregulation of 462 genes in mammary gland cells (ME-cells) of WAP-SVT/t transgenic animals. The majority of deregulated genes are cell-proliferation specific and Rb-E2F dependent, causing ME-cell proliferation and gland hyperplasia but not breast cancer formation. In the breast tumor cells, a further 207 genes are differentially expressed, most of them belonging to the cell communication category. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2514
Platform:
GPL339
12 Samples
Download data: CEL
Series
Accession:
GSE6246
ID:
200006246
2.
Full record GDS2514

Breast cancer formation in WAP-SVT/t transgenic animals

Analysis of mammary gland segments from WAP–SVT/t transgenic animals. These animals selectively synthesize the SV40 T/t antigen in mammary gland epithelial (ME) cells and develop breast cancer after the first lactation. Results provide insight into the role of SV40 T/t antigen in tumor formation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 disease state sets
Platform:
GPL339
Series:
GSE6246
12 Samples
Download data: CEL
DataSet
Accession:
GDS2514
ID:
2514
3.

[MOE430A] Affymetrix Mouse Expression 430A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Mouse Genome 430A 2.0 Array is accessioned in GEO as GPL8321. June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...
Organism:
Mus musculus
142 DataSets
423 Series
2 Related Platforms
5328 Samples
Download data
Platform
Accession:
GPL339
ID:
100000339
4.

WAP-SVT/t-LAK sample II: WAP-SVT/t mouse on the first day of lactation

Organism:
Mus musculus
Source name:
mammary gland
Platform:
GPL339
Series:
GSE6246
Dataset:
GDS2514
Download data: CEL
Sample
Accession:
GSM143904
ID:
300143904
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db=gds|term=GSM143904[Accession]|query=1|qty=2|blobid=MCID_6769cb190bdf8a6e73ef7ecd|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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