GEO DataSets

(Submitter supplied) Oligodendrocytes undergo extensive changes as they differentiate from progenitors into myelinating cells. To better understand the molecular mechanisms underlying this transformation, we performed a comparative analysis using gene expression profiling of A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes. Cells were sort-purified ex vivo from postnatal rat brain using flow cytometry. Using Affymetrix microarrays, 1707 transcripts were identified with a more than twofold increase in expression inO4+oligodendrocytes. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Datasets:

GDS2379 GDS2380

Platforms:

GPL341 GPL342

18 Samples

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Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage sets

Platform:

GPL341

Series:

GSE5940

9 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Array A of GeneChip Rat Expression Set 230 Has 15923 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. more...

Organism:

Rattus norvegicus

68 DataSets

148 Series

2 Related Platforms

3292 Samples

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