GSM1327393[Accession] - GEO DataSets

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Items: 4

Select item 2000549761.

Gene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.

(Submitter supplied) The HMG-box factor Tcf1 is required during T-cell development in the thymus and mediates the nuclear response to Wnt signals. Tcf1−/− mice have previously been characterized and show developmental blocks at the CD4−CD8− double negative (DN) to CD4+CD8+ double positive transition. Due to the blocks in T-cell development, Tcf1−/− mice normally have a very small thymus. Unexpectedly, a large proportion of Tcf1−/− mice spontaneously develop thymic lymphomas with 50% of mice developing a thymic lymphoma/leukemia at the age of 16 wk. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4867
Platform:: GPL1261
17 Samples

Download data: CEL

Series

Accession:: GSE54976

ID:: 200054976

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48672.

T-cell factor 1-deficient thymic lymphoma

Analysis of thymocytes collected from Tcf1-/- animals with thymic lymphoma. Tcf1-/- animals of similar age without tumors and Tcf1+/- animals were also examined. Tcf1 is a Wnt-responsive transcription factor. Results provide insight into the role of Tcf1 in the development of thymic lymphomas.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 2 tissue sets

Platform:: GPL1261
Series:: GSE54976
17 Samples

Download data: CEL

DataSet

Accession:: GDS4867

ID:: 4867

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...