GEO DataSets

(Submitter supplied) We analyzed the functional role of DOR (Diabetes and Obesity Regulated gene) (also named Tp53inp2) in skeletal muscle. We show that DOR has a direct impact on skeletal muscle mass in vivo. Thus, using different transgenic mouse models, we demonstrate that while muscle-specific DOR gain-of-function results in reduced muscle mass, loss-of-function causes muscle hypertrophy. DOR has been described as a protein with two different functions, i.e., a nuclear coactivator and an autophagy regulator (Baumgartner et. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS5053 GDS5054

Platform:

GPL11180

13 Samples

Download data: CEL

Analysis of quadriceps from a muscle-specific, Diabetes and Obesity Regulated gene (DOR; also named Tp53inp2) overexpression line (SKM-Tg). DOR gain of function causes a reduction in muscle mass. Results provide insight into the functional role of DOR in skeletal muscle.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL11180

Series:

GSE54917

7 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site

Organism:

Mus musculus

13 DataSets

289 Series

9 Related Platforms

7003 Samples

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