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Items: 3

1.

Effect of choline kinase inhibitor hexadecyltrimethylammonium bromide on Plasmodium falciparum gene expression

(Submitter supplied) Investigations on the fundamental of malaria parasite biology, such as invasion, growth cycle, metabolism and cell signalling have uncovered a number of potential antimalarial drug targets, including choline kinase, a key enzyme involved in the synthesis of phosphatidylcholine, an important component in parasite membrane compartment. The effect on gene expression of Plasmodium falciparum K1 strain following 72 hours exposure to 2 μM (IC50 concentration) of the choline kinase inhibitor, hexadecyltrimethylammonium bromide (HDTAB) was evaluated by DNA microarray analysis. more...
Organism:
Plasmodium falciparum; Anopheles gambiae
Type:
Expression profiling by array
Platform:
GPL1321
2 Samples
Download data: CEL
Series
Accession:
GSE54775
ID:
200054775
2.

[Plasmodium_Anopheles] Affymetrix Plasmodium/Anopheles Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 Oct 12, 2009: annotation table updated with netaffx build 32 Protocol: see manufacturer's web site The GeneChip Plasmodium/Anopheles Genome Array includes probe sets to over 4,300 Plasmodium falciparam transcripts and approximately 14,900 Anopheles gambiae transcripts. more...
Organism:
Plasmodium falciparum; Anopheles gambiae
6 DataSets
30 Series
523 Samples
Download data
Platform
Accession:
GPL1321
ID:
100001321
3.

P. falciparum K1 untreated

Organism:
Plasmodium falciparum
Source name:
Parasite trophozoites without treatment incubated for 72 hours
Platform:
GPL1321
Series:
GSE54775
Download data: CEL
Sample
Accession:
GSM1323786
ID:
301323786
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