GSM1279615[Accession] - GEO DataSets

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Items: 4

Select item 2000529691.

Expression data from Sar1 isoform overexpressing rat hepatoma cell lines

(Submitter supplied) The endoplasmic reticulum (ER) is the site of secretory lipoprotein production and de novo cholesterol synthesis, yet little is known about how these activities are coordinated with each other, or with the activity of the COPII machinery, which transports ER cargo to the Golgi. The Sar1B component of this machinery is mutated in Chylomicron Retention Disorder, establishing that this Sar1 isoform secures delivery of dietary lipids into the circulation. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS4873
Platform:: GPL1355
25 Samples

Download data: CEL

Series

Accession:: GSE52969

ID:: 200052969

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48732.

Hepatoma cell line overexpressing human Sar1 components of the coat protein complex II transport machinery

Analysis of McArdle-RH7777 hepatoma cell lines overexpressing human SAR1A, SAR1B, or a constitutively active mutant SAR1B that cannot hydrolyze GTP to support coat protein complex II (COPII) vesicle assembly. Results provide insight into roles of the SAR1 isoforms in the COPII transport machinery.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 4 genotype/variation sets

Platform:: GPL1355
Series:: GSE52969
25 Samples

Download data: CEL

DataSet

Accession:: GDS4873

ID:: 4873

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000013553.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...