GSM1275846[Accession] - GEO DataSets

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Items: 4

Select item 2000527761.

Gene expression study in CLL of B-cell receptor triggering

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL11487 GPL6480
64 Samples

Download data: TXT

Series

Accession:: GSE52776

ID:: 200052776

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000527752.

Gene expression study in CLL of B-cell receptor triggering (miRNA study)

(Submitter supplied) The B-cell receptor (BCR) plays an important role in pathogenesis and progression of chronic lymphocytic leukemia (CLL). We investigated the BCR triggering-dependent microRNA modulation by stimulating CLL cells with immobilized anti-IgM. miRome of immobilized anti-IgM stimulated CLL cells (n=16) identified a substantial upregulation of miR-132 in both unmutated (UM) and mutated (M) IGHV subgroups. A parallel gene expression profile and an in-silico analysis to identify miR-132 target genes¸ allowed us to focus on SIRT1, that encodes for a histone deacetylase targeting several proteins including TP53. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL11487
32 Samples

Download data: TXT

Series

Accession:: GSE52775

ID:: 200052775

PubMed Full text in PMC Similar studies

Select item 1000114873.

Agilent-021827 Human miRNA Microarray [miRNA_107_Sep09_2_105]

(Submitter supplied) Table corresponds to miRNA_107_Sep09_2_105 feature extraction file. Protocol: see manufacturer's web site at http://www.agilent.com/