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Items: 4

1.

Exposure to Cobalt Causes Transcriptomic and Proteomic Changes in Two Rat Liver Derived Cell Lines

(Submitter supplied) Cobalt is a transition group metal present in trace amounts in the human diet, but in larger doses it can be acutely toxic or cause adverse health effects in chronic, long term exposures. Its use in many industrial processes and alloys worldwide presents opportunities for occupational exposures, as well as exposures to military personnel. While the toxic effects of cobalt have been widely studied, the exact mechanisms of toxicity remain unclear. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS4953 GDS4954
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE51207
ID:
200051207
2.
Full record GDS4954

Cobalt effect on liver cell line MH1C1: dose response

Analysis of MH1C1 liver cells exposed to 160 or 310 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent, 3 dose sets
Platform:
GPL1355
Series:
GSE51207
12 Samples
Download data: CEL
3.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...
Organism:
Rattus norvegicus
107 DataSets
750 Series
13 Related Platforms
23059 Samples
Download data
Platform
Accession:
GPL1355
ID:
100001355
4.

MH1C1_high_rep4

Organism:
Rattus norvegicus
Source name:
MH1C1 cells exposed to 310 µM CoCl2 for 24 h
Platform:
GPL1355
Series:
GSE51207
Dataset:
GDS4954
Download data: CEL
Sample
Accession:
GSM1240501
ID:
301240501
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