GSM1232895[Accession] - GEO DataSets

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Items: 3

Select item 2000509431.

The effect of inhaled IFNbeta (SNG001) versus placebo on peripheral blood mononuclear cells during an upper respiratory tract infection

(Submitter supplied) Microarray analysis of whole blood samples (collected into PAXgene tubes from PreAnalytiX) during a phase II double-blind, randomized (1:1 ratio) clinical trial in which inhaled IFN-β (SNG001) or placebo treatment was initiated within 24 hours of asthmatics reporting cold symptoms. Patients were dosed once a day for 14 days, with samples collected at day 1 (prior to first dose), day 4 and day 7. Analysis of genome-wide gene expression (only conducted using samples from the BTS Step 4/5, mITT subgroup), showed a treatment-related enhancement of systemic innate immunity, thereby providing compelling evidence for exogenous IFN-β enhancing antiviral responses.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17077
141 Samples

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Accession:: GSE50943

ID:: 200050943

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000170772.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...