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Items: 4

1.

Novel approach to select genes from RMA normalized microarray data using functional hearing tests in aging mice.

(Submitter supplied) Presbycusis – age-related hearing loss – is the number one communicative disorder of our aged population. Here we analyzed gene expression for a set of GABA receptors in the cochlea of aging CBA mice using the Affymetrix GeneChip MOE430A. Functional phenotypic hearing measures distortion-product otoacoustic emission (DPOAE) amplitudes (four age groups) were made. The gene expression changes from RMA normalized microarray data (40 replicates) were first subjected to one-way ANOVA, and then linear regression was performed. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4925
Platform:
GPL339
41 Samples
Download data: CEL, CHP, XLS
Series
Accession:
GSE49543
ID:
200049543
2.
Full record GDS4925

Age-related hearing loss model: cochlea

Analysis of cochlea from old CBA females and males with mild or severe age-related hearing loss (presbycusis). The CBA strain it loses its hearing progressively over its lifetime. Results provide insight into the molecular mechanisms underlying presbycusis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 4 disease state, 2 gender sets
Platform:
GPL339
Series:
GSE49543
41 Samples
Download data: CEL, CHP
3.

[MOE430A] Affymetrix Mouse Expression 430A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Mouse Genome 430A 2.0 Array is accessioned in GEO as GPL8321. June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...
Organism:
Mus musculus
142 DataSets
423 Series
2 Related Platforms
5328 Samples
Download data
Platform
Accession:
GPL339
ID:
100000339
4.

CBA Cochlea Mice-35

Organism:
Mus musculus
Source name:
CBA mice cochlea
Platform:
GPL339
Series:
GSE49543
Dataset:
GDS4925
Download data: CEL, CHP
Sample
Accession:
GSM1201598
ID:
301201598
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