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Items: 4

1.

Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

(Submitter supplied) Gene expression was measured using microarrays in 8 hour postfertilization embryos, comparing control versus ethanol-treated (2 to 8 hours postfertilization) embryos. This experiment was performed to determine the gene expression changes that occur in response to ethanol treatment as a model of fetal alcohol spectrum disorder. Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic birth defects that include craniofacial, neural and cardiac defects. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Dataset:
GDS5082
Platform:
GPL1319
14 Samples
Download data: CEL, CHP
Series
Accession:
GSE48380
ID:
200048380
2.
Full record GDS5082

Fetal alcohol spectrum disorder model: whole embryo

Analysis of embryos treated with ethanol in embryo medium from 2 hours post fertilization (hpf) to 8hpf. FASD occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic developmental defects. Results provide insight into molecular basis of FASD pathogenesis.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL1319
Series:
GSE48380
14 Samples
Download data: CEL, CHP
3.

[Zebrafish] Affymetrix Zebrafish Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The Affymetrix GeneChip Zebrafish Genome Array can be used to study gene expression of over 14,900 Danio rerio transcripts. Sequence information for this array was selected from the following public data sources: RefSeq (July 2003), GenBank (release 136.0, June 2003), dbEST (July 2003), and UniGene (Build 54, June 2003). more...
Organism:
Danio rerio
18 DataSets
135 Series
1 Related Platform
1713 Samples
Download data
Platform
Accession:
GPL1319
ID:
100001319
4.

alcohol_rep8

Organism:
Danio rerio
Source name:
Total RNA from alcohol-treated embryos
Platform:
GPL1319
Series:
GSE48380
Dataset:
GDS5082
Download data: CEL, CHP
Sample
Accession:
GSM1176791
ID:
301176791
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