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Items: 4

1.

Microarray profiling of primary neurons transduced with shRNA for multiple ASD-implicated genes

(Submitter supplied) Austism spectrum disorder (ASD) is a heterogeneous behavioral disease most commonly characterized by severe impairment of social engagement and the presence of repetitive activities. The molecular etiology of ASD is still largely unknown despite a strong genetic component. Part of the difficulty in turning genetics into disease mechanisms and potentially new therapeutics is the sheer number and diversity of the genes that have been associated with ASD and ASD symptoms. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4759
Platform:
GPL1261
37 Samples
Download data: CEL
Series
Accession:
GSE47150
ID:
200047150
2.
Full record GDS4759

Embryonic primary cortical neuron response to knockdown of multiple autism candidate genes

Analysis of E16 primary cortical neuron cultures transduced with shRNA constructs of austism spectrum disorder (ASD)-implicated genes (ACGs): Mecp2, Mef2a, Mef2d, Fmr1, Nlgn1, Nlgn3, Pten, and Shank3. Results provide insight into common transcriptional networks underlying autism.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 10 protocol sets
Platform:
GPL1261
Series:
GSE47150
37 Samples
Download data: CEL
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4546 Series
40 Related Platforms
58941 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

NLGN1_4

Organism:
Mus musculus
Source name:
primary cortical neurons, NLGN1 shRNA
Platform:
GPL1261
Series:
GSE47150
Dataset:
GDS4759
Download data: CEL
Sample
Accession:
GSM1145771
ID:
301145771
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