GEO DataSets

(Submitter supplied) The outcome for children with high-grade gliomas (HGG) remains dismal, with a two-year survival rate of only 10-30%. Approximately half of pediatric HGGs are diffuse intrinsic pontine glioma (DIPG), a brainstem tumor that arises almost exclusively in children. Genome-wide analyses of copy number imbalances previously showed that platelet derived growth factor receptor alpha (PDGFRA) is the most frequent target of focal amplification in pediatric HGGs. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4821

Platform:

GPL11180

45 Samples

Download data: CEL

Analysis of high-grade gliomas (HGG) driven by intracranial implantation of p53-null astrocytes expressing any of 6 different mutant forms of platelet derived growth factor receptor alpha (Pdgfrα) found in pediatric HGGs. Results provide insight into the role of PDGFRα mutations in pediatric HGGs.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 disease state, 8 genotype/variation sets

Platform:

GPL11180

Series:

GSE46190

45 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site

Organism:

Mus musculus

13 DataSets

289 Series

9 Related Platforms

7003 Samples

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