GEO DataSets

(Submitter supplied) There is much controversy about the role of T-regulatory cells (Treg) in human colon cancer. High densities of tumor-infiltrating Treg can correlate with better or worse clinical outcomes depending on the sutdy. Treg have potent anti-inflammatory functions that have been shown to control cancer progression. However, Treg isolated from patient with colon cancer or in mouse models of polyposis do not have the ability to suppress inflammation and instead promote cancer. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4588

Platform:

GPL6246

44 Samples

Download data: CEL

Analysis of T-regulatory cells (Treg) from various organs (small intestine, spleen, mesenteric lymph node) of polyp-ridden Foxp3-GFPxAPCΔ468 reporter males. Tregs from the polyposis model promote cancer. Results provide insight into molecular mechanisms underlying these pathogenic Tregs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type, 2 genotype/variation, 5 tissue sets

Platform:

GPL6246

Series:

GSE41229

44 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Mus musculus

143 DataSets

2504 Series

28 Related Platforms

30419 Samples

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