GEO DataSets

(Submitter supplied) ß-chloroprene (2-chloro-1,3-butadiene), a monomer used in the production of neoprene elastomers, is of regulatory interest due to the production of multi-organ tumors in mouse and rat cancer bioassays. A significant increase in female mouse lung tumors was observed at the lowest exposure concentration of 12.8 ppm while a small, but not statistically significant, increase was observed in female rats only at the highest exposure concentration of 80 ppm. more...

Organism:

Mus musculus; Rattus norvegicus

Type:

Expression profiling by array

Datasets:

GDS4847 GDS4848

Platforms:

GPL1355 GPL1261

100 Samples

Download data: CEL

Analysis of lungs of B6C3F1 females exposed to 0 to 90 ppm chloroprene (CR) for 5 or 15 days. CR, a monomer used in the production of neoprene elastomers, generates multiorgan tumors in mouse and rat cancer bioassays. Compared to rats (GDS4848), B6C3F1 mice are sensitive to CR-induced lung tumors.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 agent, 5 dose, 2 time sets

Platform:

GPL1261

Series:

GSE40795

50 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4547 Series

40 Related Platforms

58950 Samples

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