GSM1000724[Accession] - GEO DataSets

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Items: 3

Select item 2000407531.

Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies

(Submitter supplied) Daptomycin is an extensively used anti-staphylococcal agent due to the rise in methicillin-resistant Staphylococcus aureus. However, both laboratory-derived and clinical decreased susceptibility isolates have been described, but the mechanism(s) of resistance is poorly understood. To further understand daptomycin resistance, comparative genome sequencing, transcriptomics, ultrastructure ,and cell envelope studies were carried out on two relatively higher level (4 and 8 ug/ml-1) laboratory-derived daptomycin-resistant strains (strains CB1541 and CB1540 respectively) compared to their methicillin-resistant parent strain (CB1118;MW2). more...

Organism:: Staphylococcus aureus

Type:: Expression profiling by array

Platform:: GPL5881
6 Samples

Download data: TXT

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Accession:: GSE40753

ID:: 200040753

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000058812.

JCVI PFGRC Staphylococcus aureus 22K v6 array designed primarily based on strain MW2

(Submitter supplied) This set includes 4440 oligonucleotides, has 22176 spots distributed in 48 blocks. Protocol: 6QSA, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000