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Items: 15

1.

Germline Chd8 haploinsufficiency alters brain development in mouse

(Submitter supplied) We examined the impact of germline heterozygous frameshift Chd8 mutation on neurodevelopment in mice. Adult Chd8+/del5 mice exhibited cognitive impairment correlated with increased cerebral cortex, hippocampus, and amygdala volume, but displayed normal social interactions and no repetitive behaviors. Network analysis of neurodevelopmental gene expression revealed widespread transcriptional changes in Chd8+/del5 mice across pathways disrupted in neurodevelopmental disorders, including neurogenesis, synaptic processes, and neuroimmune signaling. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21103 GPL13112
12 Samples
Download data: BW, NARROWPEAK, TXT
Series
Accession:
GSE99331
ID:
200099331

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 4000 (Mus musculus)

Organism:
Mus musculus
6617 Series
142181 Samples
Download data
Platform
Accession:
GPL21103
ID:
100021103

3.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8353 Series
188842 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

4.

Chd8_Input_merged

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data: BW
Sample
Accession:
GSM2644274
ID:
302644274

SRA Run Selector

5.

Chd8_ChIP_merged

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data: BW, NARROWPEAK
Sample
Accession:
GSM2644272
ID:
302644272

SRA Run Selector

6.

RNA-seq_Het.P56.adult

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644270
ID:
302644270

SRA Run Selector

7.

RNA-seq_WT.P56.adult

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644269
ID:
302644269

SRA Run Selector

8.

RNA-seq_Het.P0.Chd8

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644268
ID:
302644268

SRA Run Selector

9.

RNA-seq_WT.P0.Chd8

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644267
ID:
302644267

SRA Run Selector

10.

RNA-seq_Het.e17.5

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644266
ID:
302644266

SRA Run Selector

11.

RNA-seq_WT.e17.5

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644265
ID:
302644265

SRA Run Selector

12.

RNA-seq_Het.e14.5

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644264
ID:
302644264

SRA Run Selector

13.

RNA-seq_WT.e14.5

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644263
ID:
302644263

SRA Run Selector

14.

RNA-seq_WT.e12.5

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL21103
Series:
GSE99331
Download data
Sample
Accession:
GSM2644261
ID:
302644261

SRA Run Selector

15.

RNA-seq_Het.e12.5

Organism:
Mus musculus
Source name:
Bulk forebrain
Platform:
GPL13112
Series:
GSE99331
Download data
Sample
Accession:
GSM2644262
ID:
302644262

SRA Run Selector

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db=gds|term=GSE99331[Accession]|query=1|qty=2|blobid=MCID_674c578ed8260840385272c9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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