GSE86906[Accession] - GEO DataSets - NCBI

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Select item 2000869061.

Human iPSC glial mouse chimeras reveal glial contributions to schizophrenia

(Submitter supplied) Genetic studies have suggested a role for glial pathology in the genesis of schizophrenia (SCZ). To assess the nature of SCZ-associated human glial dysfunction in vivo, we established human glial chimeric mice using glial progenitor cells (GPCs) produced from induced pluripotential cells (hiPSCs), derived from patients with juvenile-onset schizophrenia or healthy controls. To this end, hiPSC GPCs were implanted neonatally into either immunodeficient myelin wild-type mice, in which donor GPCs remained as progenitors or became astrocytes, or into myelin-deficient shiverer mice, in which the GPCs also gave rise to oligodendrocytes. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
36 Samples

Download data: GFF3, PDF, TXT

Series

Accession:: GSE86906

ID:: 200086906

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000167912.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

12243 Series
349957 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3023445243.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344524

ID:: 302344524

SRA Run Selector

Select item 3023445234.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344523

ID:: 302344523

SRA Run Selector

Select item 3023445225.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344522

ID:: 302344522

SRA Run Selector

Select item 3023445216.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344521

ID:: 302344521

SRA Run Selector

Select item 3023445207.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344520

ID:: 302344520

SRA Run Selector

Select item 3023445198.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344519

ID:: 302344519

SRA Run Selector

Select item 3023445189.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344518

ID:: 302344518

SRA Run Selector

Select item 30234451710.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2344517

ID:: 302344517

SRA Run Selector

Select item 30231023111.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310231

ID:: 302310231

SRA Run Selector

Select item 30231023012.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310230

ID:: 302310230

SRA Run Selector

Select item 30231022913.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310229

ID:: 302310229

SRA Run Selector

Select item 30231022814.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310228

ID:: 302310228

SRA Run Selector

Select item 30231022715.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310227

ID:: 302310227

SRA Run Selector

Select item 30231022616.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310226

ID:: 302310226

SRA Run Selector

Select item 30231022517.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310225

ID:: 302310225

SRA Run Selector

Select item 30231022418.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310224

ID:: 302310224

SRA Run Selector

Select item 30231022319.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310223

ID:: 302310223

SRA Run Selector

Select item 30231022220.

Organism:: Homo sapiens

Source name:: Glial Progenitor Cell

Platform:: GPL16791
Series:: GSE86906

Sample

Accession:: GSM2310222

ID:: 302310222

SRA Run Selector

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