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Items: 18

1.

Identification of a potent and selective chemical probe for exploring the role of Mediator complex-associated protein kinases CDK8 and CDK19 in human disease [Colo205]

(Submitter supplied) There is an unmet need for chemical tools to explore the role of the Mediator complex in human pathologies ranging from cancer to cardiovascular disease. Here we determine that CCT251545 a WNT-pathway inhibitor discovered by cell-based screening is a potent and selective chemical probe for the Mediator complex-associated protein kinases CDK8 and CDK19. CCT251545 is an ATP competitive inhibitor with >100-fold selectivity over 291 other kinases. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
16 Samples
Download data: TXT
Series
Accession:
GSE67845
ID:
200067845

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...
Organism:
Homo sapiens
577 Series
1 Related Platform
9541 Samples
Download data
Platform
Accession:
GPL17077
ID:
100017077

3.

COLO205_DMSO_6H_D

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657108
ID:
301657108

4.

COLO205_DMSO_6H_C

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657107
ID:
301657107

5.

COLO205_DMSO_6H_B

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657106
ID:
301657106

6.

COLO205_DMSO_6H_A

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657105
ID:
301657105

7.

COLO205_DMSO_2H_D

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657104
ID:
301657104

8.

COLO205_DMSO_2H_C

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657103
ID:
301657103

9.

COLO205_DMSO_2H_B

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657102
ID:
301657102

10.

COLO205_DMSO_2H_A

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with DMSO for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657101
ID:
301657101

11.

COLO205_CPD_1_6H_D

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657100
ID:
301657100

12.

COLO205_CPD_1_6H_C

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657099
ID:
301657099

13.

COLO205_CPD_1_6H_B

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657098
ID:
301657098

14.

COLO205_CPD_1_6H_A

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 6H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657097
ID:
301657097

15.

COLO205_CPD_1_2H_D

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657096
ID:
301657096

16.

COLO205_CPD_1_2H_C

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657095
ID:
301657095

17.

COLO205_CPD_1_2H_B

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657094
ID:
301657094

18.

COLO205_CPD_1_2H_A

Organism:
Homo sapiens
Source name:
Colo205 colon cancer cells were treated with CPD 1 for 2H (channel 1) Stratagene Universal Human Reference RNA (channel 2)
Platform:
GPL17077
Series:
GSE67845 GSE67849
Download data: TXT
Sample
Accession:
GSM1657093
ID:
301657093

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