GSE52154[Accession] - GEO DataSets - NCBI

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Select item 2000521541.

Gene expression signature overlap between shETV1 and BRD32048 in LNCaP and SK-MEL-28

(Submitter supplied) Identification of BRD32048 as an inhibitor of ETV1 oncogenic transcription factor. This compound was indentified by small molecule mcroarray (a binding assay). It was able to consistently inhibit an ETV1-dependent MMP1-driven luciferase signal. Its direct binding was validated by Suface plasmon resonance (Biacore assay). It inhibits ETV1-driven invasion in ETV1-dependent cell lines. The goal of this gene expression comparison was to interogate the effects of BRD32048 on the global gene expression and to define the degree to which its siganture overlaps with an ETV1-specific shRNA-induced gene expression signature.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17897
33 Samples

Download data: CEL

Series

Accession:: GSE52154

ID:: 200052154

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000178972.

[HT_HG-U133A] Affymetrix Human Genome U133A Array (custom CDF: HTHGU133A_Hs_ENTREZG.cdf version 17.0.0)

(Submitter supplied) Identical to GPL3921 but used a custom CDF Protocol: see manufacturer's web site

Organism:: Homo sapiens

1 Series
1 Related Platform
33 Samples

Download data: CDF, TXT

Platform

Accession:: GPL17897

ID:: 100017897

Select item 3012603703.

SK-MEL-28.20µMBRD32048/16h.rep3

Organism:: Homo sapiens

Source name:: SK-MEL-28, 20µMBRD32048/16h, rep3

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260370

ID:: 301260370

Select item 3012603694.

SK-MEL-28.20µMBRD32048/16h.rep2

Organism:: Homo sapiens

Source name:: SK-MEL-28, 20µMBRD32048/16h, rep2

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260369

ID:: 301260369

Select item 3012603685.

SK-MEL-28.20µMBRD32048/16h.rep1

Organism:: Homo sapiens

Source name:: SK-MEL-28, 20µMBRD32048/16h, rep1

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260368

ID:: 301260368

Select item 3012603676.

SK-MEL-28.DMSO/16h.rep3

Organism:: Homo sapiens

Source name:: SK-MEL-28, DMSO control/16h, rep3

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260367

ID:: 301260367

Select item 3012603667.

SK-MEL-28.DMSO/16h.rep2

Organism:: Homo sapiens

Source name:: SK-MEL-28, DMSO control/16h, rep2

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260366

ID:: 301260366

Select item 3012603658.

SK-MEL-28.DMSO/16h.rep1

Organism:: Homo sapiens

Source name:: SK-MEL-28, DMSO control/16h, rep1

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260365

ID:: 301260365

Select item 3012603649.

SK-MEL-28.ETV1-sh5.rep3

Organism:: Homo sapiens

Source name:: SK-MEL-28, ETV1-sh5, 4 days, rep3

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260364

ID:: 301260364

Select item 30126036310.

SK-MEL-28.ETV1-sh5.rep2

Organism:: Homo sapiens

Source name:: SK-MEL-28, ETV1-sh5, 4 days, rep2

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260363

ID:: 301260363

Select item 30126036211.

SK-MEL-28.ETV1-sh5.rep1

Organism:: Homo sapiens

Source name:: SK-MEL-28, ETV1-sh5, 4 days, rep1

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260362

ID:: 301260362

Select item 30126036112.

SK-MEL-28.ETV1-sh3.rep3

Organism:: Homo sapiens

Source name:: SK-MEL-28, ETV1-sh3, 4 days, rep3

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260361

ID:: 301260361

Select item 30126036013.

SK-MEL-28.ETV1-sh3.rep2

Organism:: Homo sapiens

Source name:: SK-MEL-28, ETV1-sh3, 4 days, rep2

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260360

ID:: 301260360

Select item 30126035914.

SK-MEL-28.ETV1-sh3.rep1

Organism:: Homo sapiens

Source name:: SK-MEL-28, ETV1-sh3, 4 days, rep1

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260359

ID:: 301260359

Select item 30126035815.

SK-MEL-28.GFP-sh.rep3

Organism:: Homo sapiens

Source name:: SK-MEL-28, GFP-sh, 4 days, rep3

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260358

ID:: 301260358

Select item 30126035716.

SK-MEL-28.GFP-sh.rep2

Organism:: Homo sapiens

Source name:: SK-MEL-28, GFP-sh, 4 days, rep2

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260357

ID:: 301260357

Select item 30126035617.

SK-MEL-28.GFP-sh.rep1

Organism:: Homo sapiens

Source name:: SK-MEL-28, GFP-sh, 4 days, rep1

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260356

ID:: 301260356

Select item 30126035518.

LNCaP.872.DOX4d.rep3

Organism:: Homo sapiens

Source name:: LNCaP.872, doxicyclin 4days, rep3

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260355

ID:: 301260355

Select item 30126035419.

LNCaP.872.DOX4d.rep2

Organism:: Homo sapiens

Source name:: LNCaP.872, doxicyclin 4days, rep2

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260354

ID:: 301260354

Select item 30126035320.

LNCaP.872.DOX4d.rep1

Organism:: Homo sapiens

Source name:: LNCaP.872, doxicyclin 4days, rep1

Platform:: GPL17897
Series:: GSE52154

Download data: CEL

Sample

Accession:: GSM1260353

ID:: 301260353

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