GSE4636[Accession] - GEO DataSets - NCBI

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Select item 2000046361.

Differential redulation of gene expression by an RTI SARM and canonical agonist of androgen receptor

(Submitter supplied) We have previously identified a family of novel androgen receptor (AR) ligands that, upon binding, enable AR to adopt structures distinct from that observed in the presence of canonical agonists. In this report, we describe the use of these compounds to establish a relationship between AR structure and biological activity with a view to defining a rational approach with which to identify useful Selective Androgen Receptor Modulators (SARMs). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2057 GDS2058
Platforms:: GPL97 GPL96
36 Samples

Download data: CEL

Series

Accession:: GSE4636

ID:: 200004636

PubMed Similar studies Analyze with GEO2R

Select item 20582.

Full record GDS2058

Androgen receptor modulator effect: time course (HG-U133B)

Analysis of LNCaP cells treated for 6 and 24 hours with RTI-018, an androgen receptor (AR) ligand with a mechanism of action different from that of canonical agonists. Results provide insight into the link between RTI-018 induced AR conformational changes and its ability to regulate gene expression.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 2 time sets

Platform:: GPL97
Series:: GSE4636
18 Samples

Download data: CEL

DataSet

Accession:: GDS2058

ID:: 2058

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 20573.

Full record GDS2057

Androgen receptor modulator effect: time course (HG-U133A)

Analysis of LNCaP cells treated for 6 and 24 hours with RTI-018, an androgen receptor (AR) ligand with a mechanism of action different from that of canonical agonists. Results provide insight into the link between RTI-018 induced AR conformational changes and its ability to regulate gene expression.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 2 time sets

Platform:: GPL96
Series:: GSE4636
18 Samples

Download data: CEL

DataSet

Accession:: GDS2057

ID:: 2057

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 1000000964.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...

Organism:: Homo sapiens

364 DataSets
1125 Series
11 Related Platforms
42430 Samples

Platform

Accession:: GPL96

ID:: 100000096

Select item 1000000975.

[HG-U133B] Affymetrix Human Genome U133B Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...

Organism:: Homo sapiens

51 DataSets
165 Series
2 Related Platforms
7917 Samples

Platform

Accession:: GPL97

ID:: 100000097

Select item 3001040846.

Treatment: 018; time: 24 hrs; repeat: 3; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM104084

ID:: 300104084

Select item 3001040837.

Treatment: DHT; time: 24 hrs; repeat: 3; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM104083

ID:: 300104083

Select item 3001040798.

Treatment: vehicle; time: 24 hrs; repeat: 3; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM104079

ID:: 300104079

Select item 3001040739.

Treatment: 018; time: 24 hrs; repeat: 2; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM104073

ID:: 300104073

Select item 30010407110.

Treatment: DHT; time: 24 hrs; repeat: 2; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM104071

ID:: 300104071

Select item 30006486611.

Treatment: RTI-6413-018; time: 24 hrs; repeat: 3

Organism:: Homo sapiens

Source name:: LNCaP cells

Platform:: GPL96
Series:: GSE4636
Dataset:: GDS2057

Download data: CEL

Sample

Accession:: GSM64866

ID:: 300064866

Select item 30010378012.

Treatment: vehicle; time 24 hrs; repeat: 2; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM103780

ID:: 300103780

Select item 30006486513.

Treatment: DHT; time: 24 hrs; repeat: 3

Organism:: Homo sapiens

Source name:: LNCaP cells

Platform:: GPL96
Series:: GSE4636
Dataset:: GDS2057

Download data: CEL

Sample

Accession:: GSM64865

ID:: 300064865

Select item 30010377914.

Treatment: 018; time 6 hrs; repeat: 3; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM103779

ID:: 300103779

Select item 30006486415.

Treatment: vehicle; time 24 hrs; repeat: 3

Organism:: Homo sapiens

Source name:: LNCaP cells

Platform:: GPL96
Series:: GSE4636
Dataset:: GDS2057

Download data: CEL

Sample

Accession:: GSM64864

ID:: 300064864

Select item 30010377816.

Treatment: DHT; time 6 hrs; repeat: 3; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM103778

ID:: 300103778

Select item 30006486317.

Treatment: RTI-6413-018; time: 6 hrs; repeat: 3

Organism:: Homo sapiens

Source name:: LNCaP cells

Platform:: GPL96
Series:: GSE4636
Dataset:: GDS2057

Download data: CEL

Sample

Accession:: GSM64863

ID:: 300064863

Select item 30010355618.

Treatment: vehicle; time: 6 hrs; repeat: 3; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM103556

ID:: 300103556

Select item 30006486219.

Treatment: DHT; time: 6 hrs; repeat: 3

Organism:: Homo sapiens

Source name:: LNCaP cells

Platform:: GPL96
Series:: GSE4636
Dataset:: GDS2057

Download data: CEL

Sample

Accession:: GSM64862

ID:: 300064862

Select item 30010355520.

Treatment: 018; time: 6 hrs; repeat: 2; chip B

Organism:: Homo sapiens

Source name:: LNCaP cells; Human, prostate carcinoma, metastasized to lymph node; Maintained in DMEM/8% charcoal-stripped serum for 3 days before treatment.

Platform:: GPL97
Series:: GSE4636
Dataset:: GDS2058

Download data: CEL

Sample

Accession:: GSM103555

ID:: 300103555

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