GSE264648[Accession] - GEO DataSets - NCBI

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Select item 2002646481.

Characterization of premature cell senescence in Alzheimer’s disease using single nuclear transcriptomics

(Submitter supplied) Aging is associated with cell senescence and is the major risk factor for AD. We characterized premature cell senescence in post mortem brains from non-diseased controls (NDC) and donors with Alzheimer’s disease (AD) using imaging mass cytometry (IMC) and single nuclear RNA (snRNA) sequencing (>200,000 nuclei). We found increases in numbers of glia immunostaining for galactosidase beta (>4-fold) and p16INK4A (up to 2-fold) with AD relative to NDC. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
49 Samples

Download data: RDS

Series

Accession:: GSE264648

ID:: 200264648

Select item 1000203012.

Illumina HiSeq 4000 (Homo sapiens)

Organism:: Homo sapiens

8526 Series
195705 Samples

Platform

Accession:: GPL20301

ID:: 100020301

Select item 3082245263.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224526

ID:: 308224526

Select item 3082245254.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224525

ID:: 308224525

Select item 3082245245.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224524

ID:: 308224524

Select item 3082245236.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224523

ID:: 308224523

Select item 3082245227.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224522

ID:: 308224522

Select item 3082245218.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224521

ID:: 308224521

Select item 3082245209.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224520

ID:: 308224520

Select item 30822451910.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224519

ID:: 308224519

Select item 30822451811.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224518

ID:: 308224518

Select item 30822451712.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224517

ID:: 308224517

Select item 30822451613.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224516

ID:: 308224516

Select item 30822451514.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224515

ID:: 308224515

Select item 30822451415.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224514

ID:: 308224514

Select item 30822451316.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224513

ID:: 308224513

Select item 30822451217.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224512

ID:: 308224512

Select item 30822451118.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224511

ID:: 308224511

Select item 30822451019.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224510

ID:: 308224510

Select item 30822450920.

Organism:: Homo sapiens

Source name:: Brain

Platform:: GPL20301
Series:: GSE264648

Sample

Accession:: GSM8224509

ID:: 308224509

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