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Items: 6

1.

LARP3, LARP7, and MePCE are Involved in the Early Stage of Human Telomerase RNA Biogenesis

(Submitter supplied) Human telomerase assembly is a highly dynamic process. Using biochemical approaches, we found that LARP3 and LARP7/MePCE are involved in the early stage and that their binding to hTR is destabilized when the mature hTR is produced. LARP3 plays a negative role in preventing the processing of the 3′-extended long (exL) form and binding of LARP7 and MePCE. Interestingly, the tertiary structure of the exL form prevents LARP3 binding and facilitates hTR biogenesis. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34284
4 Samples
Download data: TSV
Series
Accession:
GSE262590
ID:
200262590
2.

Illumina NovaSeq X Plus (Homo sapiens)

Platform
Accession:
GPL34284
ID:
100034284
3.

HeLa cells, sh-MePCE-3

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL34284
Series:
GSE262590
Download data: TSV
Sample
Accession:
GSM8172113
ID:
308172113
4.

HeLa cells, sh-LARP7-3

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL34284
Series:
GSE262590
Download data: TSV
Sample
Accession:
GSM8172112
ID:
308172112
5.

HeLa cells, sh-PARN-3

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL34284
Series:
GSE262590
Download data: TSV
Sample
Accession:
GSM8172111
ID:
308172111
6.

HeLa cells, sh-Luc-1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL34284
Series:
GSE262590
Download data: TSV
Sample
Accession:
GSM8172110
ID:
308172110
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Supplemental Content

db=gds|term=GSE262590[Accession]|query=1|qty=2|blobid=MCID_675deab01afe4541ed4b6946|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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