GSE250137[Accession] - GEO DataSets - NCBI

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Select item 2002501371.

METTL14-mediated m6A differentially orchestrates brown and white adipose tissue transcriptomes to regulate systemic metabolism

(Submitter supplied) Human brown and white adipocytes (hBAT and hWAT) display markedly distinct m6A landscapes; besides, in insulin-resistant humans and mice, methyltransferase like 14 (METTL14) expression differs significantly between BAT and WAT in the context of its correlation with insulin sensitivity. We therefore employed independent BAT- and WAT-specific METTL14 knockout models to unveil the cell-type specificity of m6A mRNA methylation. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:: GPL24247 GPL24676
58 Samples

Download data: CSV

Series

Accession:: GSE250137

ID:: 200250137

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

17332 Series
938403 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 1000242473.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

14540 Series
700496 Samples

Platform

Accession:: GPL24247

ID:: 100024247

Select item 3079744464.

human white adipocyte cell line, Mettl14 KD, m6A IP, biol rep 3

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974446

ID:: 307974446

SRA Run Selector

Select item 3079744455.

human white adipocyte cell line, Mettl14 KD, m6A IP, biol rep 2

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974445

ID:: 307974445

SRA Run Selector

Select item 3079744446.

human white adipocyte cell line, Mettl14 KD, m6A IP, biol rep 1

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974444

ID:: 307974444

SRA Run Selector

Select item 3079744437.

human white adipocyte cell line, Mettl14 KD, input, biol rep 3

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974443

ID:: 307974443

SRA Run Selector

Select item 3079744428.

human white adipocyte cell line, Mettl14 KD, input, biol rep 2

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974442

ID:: 307974442

SRA Run Selector

Select item 3079744419.

human white adipocyte cell line, Mettl14 KD, input, biol rep 1

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974441

ID:: 307974441

SRA Run Selector

Select item 30797444010.

human white adipocyte cell line, Mettl14 KO, m6A IP, biol rep 4

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974440

ID:: 307974440

SRA Run Selector

Select item 30797443911.

human white adipocyte cell line, Mettl14 KO, m6A IP, biol rep 3

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974439

ID:: 307974439

SRA Run Selector

Select item 30797443812.

human white adipocyte cell line, Mettl14 KO, m6A IP, biol rep 2

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974438

ID:: 307974438

SRA Run Selector

Select item 30797443713.

human white adipocyte cell line, Mettl14 KO, m6A IP, biol rep 1

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974437

ID:: 307974437

SRA Run Selector

Select item 30797443614.

human white adipocyte cell line, Control, m6A IP, biol rep 3

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974436

ID:: 307974436

SRA Run Selector

Select item 30797443515.

human white adipocyte cell line, Control, m6A IP, biol rep 2

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974435

ID:: 307974435

SRA Run Selector

Select item 30797443416.

human white adipocyte cell line, Control, m6A IP, biol rep 1

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974434

ID:: 307974434

SRA Run Selector

Select item 30797443317.

human white adipocyte cell line, Mettl14 KO, input, biol rep 4

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974433

ID:: 307974433

SRA Run Selector

Select item 30797443218.

human white adipocyte cell line, Mettl14 KO, input, biol rep 3

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974432

ID:: 307974432

SRA Run Selector

Select item 30797443119.

human white adipocyte cell line, Mettl14 KO, input, biol rep 2

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974431

ID:: 307974431

SRA Run Selector

Select item 30797443020.

human white adipocyte cell line, Mettl14 KO, input, biol rep 1

Organism:: Homo sapiens

Source name:: white adipocyte cell

Platform:: GPL24676
Series:: GSE250137

Sample

Accession:: GSM7974430

ID:: 307974430

SRA Run Selector

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