GEO DataSets

(Submitter supplied) Type 2 diabetes (T2D) is the most common form of diabetes in humans and is closely associated with dyslipidemia and obesity that magnifies the mortality and morbidity related to T2D. The TALLYHO/JngJ (TH) mouse is a polygenic model for T2D characterized by obesity, hyperinsulinemia, impaired glucose uptake and tolerance, hyperlipidemia, and hyperglycemia. To determine the genetic factors that contribute to these T2D related characteristics in TH mice, we interbred TH mice with C57BL/6J (B6) mice. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4000

Platform:

GPL1261

64 Samples

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Analysis of various tissues from TH x B6 F2 males with high triglycerides. TH mice are a polygenic model for type 2 diabetes (T2D) characterized by obesity, insulin resistance, and hyperlipidemia. Results provide insight into quantitative trait loci (QTLs) affecting hypertriglyceridemia in TH mice.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 disease state, 4 tissue sets

Platform:

GPL1261

Series:

GSE24637

64 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4546 Series

40 Related Platforms

58941 Samples

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