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Items: 12

1.

Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction [6 wks]

(Submitter supplied) Myocardial fibrosis leads to cardiac dysfunction and arrhythmias in heart failure with preserved ejection fraction (HFpEF), but the underlying mechanisms remain poorly understood. Here, RNA sequencing identifies Forkhead Box1 (FoxO1) signaling as abnormal in HFpEF hearts. Genetic suppression of FoxO1 alters the intercellular communication between cardiomyocytes and fibroblasts, alleviates abnormal diastolic relaxation, and reduces arrhythmias. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
10 Samples
Download data: TXT
Series
Accession:
GSE240400
ID:
200240400
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

HFpEF 5

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697535
ID:
307697535
4.

HFpEF 4

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697534
ID:
307697534
5.

HFpEF 3

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697533
ID:
307697533
6.

HFpEF 2

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697532
ID:
307697532
7.

HFpEF 1

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697531
ID:
307697531
8.

Control 5

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697530
ID:
307697530
9.

Control 4

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697529
ID:
307697529
10.

Control 3

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697528
ID:
307697528
11.

Control 2

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697527
ID:
307697527
12.

Control 1

Organism:
Mus musculus
Source name:
Left ventricle
Platform:
GPL24247
Series:
GSE240400 GSE240404
Download data
Sample
Accession:
GSM7697526
ID:
307697526
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Supplemental Content

db=gds|term=GSE240400[Accession]|query=1|qty=2|blobid=MCID_674c429396d9ad0406234ab1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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