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Items: 6

1.

ARID1A suppresses R-loop mediated STING-Type I Interferon pathway activation of anti-tumor immunity (scRNA/TCR-seq)

(Submitter supplied) Clinical trials have identified ARID1A mutations as enriched among patients who respond favorably to Immune Checkpoint Blockade (ICB) in several solid tumor types independent of microsatellite instability. We show that ARID1A loss in murine models is sufficient to induce anti-tumor immune phenotypes observed in ARID1A mutant human cancers, including increased CD8+ T cell infiltration and cytolytic activity. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30172
4 Samples
Download data: MTX, TSV
Series
Accession:
GSE217806
ID:
200217806
2.

NextSeq 2000 (Mus musculus)

Platform
Accession:
GPL30172
ID:
100030172
3.

sgArid1a_CD8_T_cell_scRNA_rep2

Organism:
Mus musculus
Source name:
B16F10 Tumor
Platform:
GPL30172
Series:
GSE217806 GSE217807
Download data: MTX, TSV
Sample
Accession:
GSM6727010
ID:
306727010
4.

sgArid1a_CD8_T_cell_scRNA_rep1

Organism:
Mus musculus
Source name:
B16F10 Tumor
Platform:
GPL30172
Series:
GSE217806 GSE217807
Download data: MTX, TSV
Sample
Accession:
GSM6727009
ID:
306727009
5.

sgScr_CD8_T_cell_scRNA_rep2

Organism:
Mus musculus
Source name:
B16F10 Tumor
Platform:
GPL30172
Series:
GSE217806 GSE217807
Download data: MTX, TSV
Sample
Accession:
GSM6727008
ID:
306727008
6.

sgScr_CD8_T_cell_scRNA_rep1

Organism:
Mus musculus
Source name:
B16F10 Tumor
Platform:
GPL30172
Series:
GSE217806 GSE217807
Download data: MTX, TSV
Sample
Accession:
GSM6727007
ID:
306727007
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Supplemental Content

db=gds|term=GSE217806[Accession]|query=1|qty=2|blobid=MCID_67595496c087e3673297d067|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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