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Items: 1 to 20 of 38

1.

The NMD endonuclease SMG6 co-operates with the piRNA pathway in germ granules to shape the male germ cell transcriptome

(Submitter supplied) Nonsense-mediated RNA decay (NMD) is a conserved RNA turnover pathway. Here we report that the sole endonuclease in the NMD pathway, SMG6, is essential for the male germline. Germ-cell conditional knockout (cKO) of Smg6 causes complete arrest of spermatogenesis at the early haploid cell stage. Smg6-cKO round spermatids accumulate NMD target mRNAs with long 3’ untranslated regions (UTRs) and fail to eliminate transcripts normally expressed during meiosis, the previous step in spermatogenesis. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL24247 GPL21493
35 Samples
Download data: TXT
Series
Accession:
GSE182518
ID:
200182518
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
4.

smallRNA-seq CTRL Spc 5

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530731
ID:
305530731
5.

smallRNA-seq CTRL Spc 4

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530730
ID:
305530730
6.

smallRNA-seq CTRL Spc 3

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530729
ID:
305530729
7.

smallRNA-seq CTRL Spc 2

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530728
ID:
305530728
8.

smallRNA-seq CTRL Spc 1

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530727
ID:
305530727
9.

smallRNA-seq cKO Spc 5

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530726
ID:
305530726
10.

smallRNA-seq cKO Spc 4

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530725
ID:
305530725
11.

smallRNA-seq cKO Spc 3

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530724
ID:
305530724
12.

smallRNA-seq cKO Spc 2

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530723
ID:
305530723
13.

smallRNA-seq cKO Spc 1

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530722
ID:
305530722
14.

smallRNA-seq CTRL RS 3

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530721
ID:
305530721
15.

smallRNA-seq CTRL RS 2

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530720
ID:
305530720
16.

smallRNA-seq CTRL RS 1

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530719
ID:
305530719
17.

smallRNA-seq cKO RS 3

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530718
ID:
305530718
18.

smallRNA-seq cKO RS 2

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530717
ID:
305530717
19.

smallRNA-seq cKO RS 1

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530716
ID:
305530716
20.

RNA-seq cKO Spc 3

Organism:
Mus musculus
Source name:
testis
Platform:
GPL21493
Series:
GSE182518
Download data
Sample
Accession:
GSM5530715
ID:
305530715
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Supplemental Content

db=gds|term=GSE182518[Accession]|query=1|qty=2|blobid=MCID_67497f714e6f392e2641507d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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