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Items: 10

1.

SPOP mutations derived from prostate cancer establish a DNA hypermethylation epigenome through stabilizing GLP histone methyltransferase [methylation array]

(Submitter supplied) Abnormal DNA methylation is one of the major factors driving oncogenesis and therapy resistance in cancer. The CULLIN3-RBX1 E3 ubiquitin ligase adaptor gene SPOP is the most frequently mutated gene in primary prostate cancers (PCa). SPOP-mutated prostate tumors strikingly associate with strongly elevated levels of genome-wide DNA hypermethylation, although the underlying mechanism remains elusive.We use Illumina Infinium MethylationEPIC BeadChip to depict DNA methylation in control and SPOP F102C stabily expressed 22Rv1 cells. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL23976
8 Samples
Download data: IDAT, TSV
Series
Accession:
GSE179234
ID:
200179234

PubMed Full text in PMC Similar studies

2.

Illumina Infinium HumanMethylation850 BeadChip

(Submitter supplied) See manufacturer's website
Organism:
Homo sapiens
281 Series
1 Related Platform
16960 Samples
Download data
Platform
Accession:
GPL23976
ID:
100023976

3.

F102C-4

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411978
ID:
305411978

4.

F102C-3

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411977
ID:
305411977

5.

F102C-2

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411976
ID:
305411976

6.

F102C-1

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411975
ID:
305411975

7.

EV-4

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411974
ID:
305411974

8.

EV-3

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411973
ID:
305411973

9.

EV-2

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411972
ID:
305411972

10.

EV-1

Organism:
Homo sapiens
Source name:
Prostate
Platform:
GPL23976
Series:
GSE179234
Download data: IDAT
Sample
Accession:
GSM5411971
ID:
305411971

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db=gds|term=GSE179234[Accession]|query=1|qty=2|blobid=MCID_674b3e02362d800246182da1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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