GEO DataSets

(Submitter supplied) Purpose: to evaluate changes in the transcriptome of hippocampal cells during the course of epileptogenesis, from the early events post status epilepticus (SE) to the onset of recurrent spontaneous seizures. Experimental Design: Gene expression profiling was analyzed in hippocampi of rats subjected to the pilocarpine model of epilepsy at different times during the course of epileptogenesis: 3 days post-SE (3D), 7 days post-SE (7D), and immediately (up to 12h) after the first spontaneous seizure (Chronic). more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3827

Platform:

GPL2896

18 Samples

Download data: TXT

Analysis of hippocampal cells from Wistar adult males treated with pilocarpine during the course of epileptogenesis: 3 days post-status epilepticus (D3), D7, and immediately after the first spontaneous seizure (Chronic). Results provide insight into molecular mechanisms involved in epileptogenesis.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent, 3 time sets

Platform:

GPL2896

Series:

GSE14763

18 Samples

Download data: TXT

(Submitter supplied) Well-annotated mRNA or coding sequences were chosen to ensure usefulness for a large range of applications in basic research, biotechnology, and drug development. Each sequence was carefully screened to ensure high-quality, specific probe design, and to reduce redundancy of gene targets. All of the probes designed to these sequences were functionally tested, and over 95% were functionally validated against 10 rat tissues to ensure best representation of the gene and biologically relevant results. more...

Organism:

Rattus norvegicus

3 DataSets

21 Series

353 Samples

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