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Items: 1 to 20 of 21

1.

Recognition of cellular RNAs by the S9.6 antibody creates pervasive artifacts when imaging RNA:DNA hybrids

(Submitter supplied) We showed that the majority of the signal observed in S9.6 immunofluorescence microscopy images of fixed human cells arises from RNA, not RNA:DNA hybrids. S9.6 staining is quantitatively unchanged by pre-treatment with the human RNA:DNA hybrid-specific nuclease, RNase H1, despite experimental verification that the enzyme was active in situ. S9.6 staining was, however, significantly sensitive to pre-treatments with RNase T1, and in some cases RNase III, two ribonucleases that specifically degrade single-stranded and double-stranded RNA, respectively. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL20301 GPL21290
18 Samples
Download data: BW
Series
Accession:
GSE141833
ID:
200141833

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 3000 (Homo sapiens)

Organism:
Homo sapiens
1138 Series
28241 Samples
Download data
Platform
Accession:
GPL21290
ID:
100021290

3.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8522 Series
195588 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

4.

Mock (NV1LS2)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213966
ID:
304213966

SRA Run Selector

5.

Mock (NV1LS1)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213965
ID:
304213965

SRA Run Selector

6.

RNase T1+III (LS5J)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213961
ID:
304213961

SRA Run Selector

7.

RNase III (LS5I)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213960
ID:
304213960

SRA Run Selector

8.

RNase T1 (LS5H)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213959
ID:
304213959

SRA Run Selector

9.

Mock (LS5G)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213958
ID:
304213958

SRA Run Selector

10.

RNase T1+III (LS5F)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213957
ID:
304213957

SRA Run Selector

11.

RNase T1 (LS5D)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213956
ID:
304213956

SRA Run Selector

12.

Mock (LS5C)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL20301
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213955
ID:
304213955

SRA Run Selector

13.

RNase H1 (LS78D)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213964
ID:
304213964

SRA Run Selector

14.

Mock (LS78B)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213963
ID:
304213963

SRA Run Selector

15.

Mock (LS78A)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213962
ID:
304213962

SRA Run Selector

16.

RNase T1+III (DG3L)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213954
ID:
304213954

SRA Run Selector

17.

RNase III (DG3K)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213953
ID:
304213953

SRA Run Selector

18.

RNase T1 (DG3J)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213952
ID:
304213952

SRA Run Selector

19.

RNase T1+III (DG3I)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213951
ID:
304213951

SRA Run Selector

20.

RNase III (DG3H)

Organism:
Homo sapiens
Source name:
NTREA-2 D1
Platform:
GPL21290
Series:
GSE141833
Download data: BW
Sample
Accession:
GSM4213950
ID:
304213950

SRA Run Selector

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