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Items: 1 to 20 of 36

1.

De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG island (RRBS)

(Submitter supplied) The aberrant gain of DNA methylation at CpG islands (CGIs) is frequently observed in colorectal tumours and may silence the expression of tumour suppressors such as MLH1. Current models propose that these CGIs are targeted by de novo DNA methyltransferases (DNMTs) in a sequence-specific manner but this has not been tested. Using ectopically integrated CGIs, we find that aberrantly methylated CGIs are subject to low levels of de novo DNMT activity in colorectal cancer cells. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL18573
34 Samples
Download data: BIGWIG, COV
Series
Accession:
GSE137812
ID:
200137812

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12602 Series
343758 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

HCT116_DNMT1_KO_untreated_day_40

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088856
ID:
304088856

SRA Run Selector

4.

HCT116_DNMT1_KO_aza_treated_day_40

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088855
ID:
304088855

SRA Run Selector

5.

HCT116_DNMT1_KO_aza_treated_day_22

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088854
ID:
304088854

SRA Run Selector

6.

HCT116_DNMT1_KO_aza_treated_day_16

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088853
ID:
304088853

SRA Run Selector

7.

HCT116_DNMT1_KO_aza_treated_day_13

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088852
ID:
304088852

SRA Run Selector

8.

HCT116_DNMT1_KO_aza_treated_day_6

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088851
ID:
304088851

SRA Run Selector

9.

HCT116_DNMT1_KO_aza_treated_day_3

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088850
ID:
304088850

SRA Run Selector

10.

HCT116_DNMT1_KO

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088849
ID:
304088849

SRA Run Selector

11.

HCT116_DNMT3B_KO_untreated_day_40

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088848
ID:
304088848

SRA Run Selector

12.

HCT116_DNMT3B_KO_aza_treated_day_40

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088847
ID:
304088847

SRA Run Selector

13.

HCT116_DNMT3B_KO_aza_treated_day_28

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088846
ID:
304088846

SRA Run Selector

14.

HCT116_DNMT3B_KO_aza_treated_day_22

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088845
ID:
304088845

SRA Run Selector

15.

HCT116_DNMT3B_KO_aza_treated_day_16

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088844
ID:
304088844

SRA Run Selector

16.

HCT116_DNMT3B_KO_aza_treated_day_13

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088843
ID:
304088843

SRA Run Selector

17.

HCT116_DNMT3B_KO_aza_treated_day_6

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088842
ID:
304088842

SRA Run Selector

18.

HCT116_DNMT3B_KO_aza_treated_day_3

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088841
ID:
304088841

SRA Run Selector

19.

HCT116_DNMT3B_KO

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088840
ID:
304088840

SRA Run Selector

20.

HCT116_untreated_day_40

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL18573
Series:
GSE137812 GSE158406
Download data: BIGWIG, COV
Sample
Accession:
GSM4088839
ID:
304088839

SRA Run Selector

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