GSE131613[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2001316131.

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress [Mus musculus]

(Submitter supplied) Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPRmt). However, how different layers of UPRmt regulators are orchestrated to transcriptionally activate the stress responses remains largely unknown. Here we identified CBP-1, the worm ortholog of the mammalian acetyltransferases CBP/p300, as an essential regulator for UPRmt activation, as well as for mitochondrial stress-induced immune response, amyloid-β aggregation reduction and lifespan extension in Caenorhabditis elegans. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL23479
12 Samples

Download data: XLSX

Series

Accession:: GSE131613

ID:: 200131613

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000234792.

BGISEQ-500 (Mus musculus)

Organism:: Mus musculus

742 Series
9188 Samples

Platform

Accession:: GPL23479

ID:: 100023479

Select item 3037909733.

CBP/p300 KO + Dox_rep3

Organism:: Mus musculus

Source name:: CBP/p300 KO + Dox_rep3

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790973

ID:: 303790973

SRA Run Selector

Select item 3037909724.

CBP/p300 KO + Dox_rep2

Organism:: Mus musculus

Source name:: CBP/p300 KO + Dox_rep2

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790972

ID:: 303790972

SRA Run Selector

Select item 3037909715.

CBP/p300 KO + Dox_rep1

Organism:: Mus musculus

Source name:: CBP/p300 KO + Dox_rep1

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790971

ID:: 303790971

SRA Run Selector

Select item 3037909706.

Organism:: Mus musculus

Source name:: WT + Dox_rep3

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790970

ID:: 303790970

SRA Run Selector

Select item 3037909697.

Organism:: Mus musculus

Source name:: WT + Dox_rep2

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790969

ID:: 303790969

SRA Run Selector

Select item 3037909688.

Organism:: Mus musculus

Source name:: WT + Dox_rep1

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790968

ID:: 303790968

SRA Run Selector

Select item 3037909679.

CBP/p300 KO + DMSO_rep3

Organism:: Mus musculus

Source name:: CBP/p300 KO + DMSO_rep3

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790967

ID:: 303790967

SRA Run Selector

Select item 30379096610.

CBP/p300 KO + DMSO_rep2

Organism:: Mus musculus

Source name:: CBP/p300 KO + DMSO_rep2

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790966

ID:: 303790966

SRA Run Selector

Select item 30379096511.

CBP/p300 KO + DMSO_rep1

Organism:: Mus musculus

Source name:: CBP/p300 KO + DMSO_rep1

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790965

ID:: 303790965

SRA Run Selector

Select item 30379096412.

Organism:: Mus musculus

Source name:: WT + DMSO_rep3

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790964

ID:: 303790964

SRA Run Selector

Select item 30379096313.

Organism:: Mus musculus

Source name:: WT + DMSO_rep2

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790963

ID:: 303790963

SRA Run Selector

Select item 30379096214.

Organism:: Mus musculus

Source name:: WT + DMSO_rep1

Platform:: GPL23479
Series:: GSE131613 GSE131616

Sample

Accession:: GSM3790962

ID:: 303790962

SRA Run Selector

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