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Items: 18

1.

Effect of DGAT loss on hypoxic tumor cells growing under serum-deprived conditions

(Submitter supplied) The metabolic enzyme diglyceride acyltransferase (DGAT) is responsible for the synthesis of triglycerides. Loss of its expression may sensitize cells to conditions of nutrient and oxygen that are commonly present in tumors. This study is designed to identify stress response pathways that may be induced following the shRNA-mediated knockdown of the two genes coding for the DGAT enzymes. In vitro growth conditions lacking serum and oxygen were used to mimic growth conditions commonly found in poorly perfused tumor domains We used a microarray study to identify global transcriptional changes in kidney cancer cells (A498) grown under serum deprived conditions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17586
16 Samples
Download data: CEL
Series
Accession:
GSE117775
ID:
200117775

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]

(Submitter supplied) #%create_date=Wed Jan 22 15:39:59 2014 PST #%chip_type=HTA-2_0 #%lib_set_name=HTA-2_0 #%lib_set_version=r1 #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg19 #%genome-lifted_from-version-ncbi=GRCh37 #%netaffx-annotation-date=2013-10-15 #%netaffx-annotation-netaffx-build=34 Protocol: See manufacturers website
Organism:
Homo sapiens
639 Series
11 Related Platforms
19413 Samples
Download data
Platform
Accession:
GPL17586
ID:
100017586

3.

A498 DGAT1/2 shRNA cells, doxycycline treatment, hypoxia, biol repl 4

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308620
ID:
303308620

4.

A498 DGAT1/2 shRNA cells, doxycycline treatment, hypoxia, biol repl 3

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308619
ID:
303308619

5.

A498 DGAT1/2 shRNA cells, doxycycline treatment, hypoxia, biol repl 2

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308618
ID:
303308618

6.

A498 DGAT1/2 shRNA cells, doxycycline treatment, hypoxia, biol repl 1

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308617
ID:
303308617

7.

A498 DGAT1/2 shRNA cells, doxycycline treatment, normoxia, biol repl 4

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308616
ID:
303308616

8.

A498 DGAT1/2 shRNA cells, doxycycline treatment, normoxia, biol repl 3

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308615
ID:
303308615

9.

A498 DGAT1/2 shRNA cells, doxycycline treatment, normoxia, biol repl 2

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308614
ID:
303308614

10.

A498 DGAT1/2 shRNA cells, doxycycline treatment, normoxia, biol repl 1

Organism:
Homo sapiens
Source name:
A498 expressing induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308613
ID:
303308613

11.

A498 DGAT1/2 shRNA cells, vehicle treatment, hypoxia, biol repl 4

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308612
ID:
303308612

12.

A498 DGAT1/2 shRNA cells, vehicle treatment, hypoxia, biol repl 3

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308611
ID:
303308611

13.

A498 DGAT1/2 shRNA cells, vehicle treatment, hypoxia, biol repl 2

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308610
ID:
303308610

14.

A498 DGAT1/2 shRNA cells, vehicle treatment, hypoxia, biol repl 1

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and hypoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308609
ID:
303308609

15.

A498 DGAT1/2 shRNA cells, vehicle treatment, normoxia, biol repl 4

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308608
ID:
303308608

16.

A498 DGAT1/2 shRNA cells, vehicle treatment, normoxia, biol repl 3

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308607
ID:
303308607

17.

A498 DGAT1/2 shRNA cells, vehicle treatment, normoxia, biol repl 2

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308606
ID:
303308606

18.

A498 DGAT1/2 shRNA cells, vehicle treatment, normoxia, biol repl 1

Organism:
Homo sapiens
Source name:
A498 expressing non-induced DGAT1/2 shRNA construct grown under serum deprivation and normoxia
Platform:
GPL17586
Series:
GSE117775
Download data: CEL
Sample
Accession:
GSM3308605
ID:
303308605

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