GEO DataSets

(Submitter supplied) Using the streptozotocin-induced rat model of diabetes, levels of retinal permeability, caspase activity, and gene expression were examined after 1 and 3 months of diabetes. Gene expression changes were identified by whole genome microarray and confirmed by qPCR in the same set of animals as used in the microarray analyses and subsequently validated in independent sets of animals. Significantly more and larger magnitude gene expression changes were observed after 3 months than after 1 month of diabetes.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL2896

24 Samples

Download data: TXT

(Submitter supplied) Well-annotated mRNA or coding sequences were chosen to ensure usefulness for a large range of applications in basic research, biotechnology, and drug development. Each sequence was carefully screened to ensure high-quality, specific probe design, and to reduce redundancy of gene targets. All of the probes designed to these sequences were functionally tested, and over 95% were functionally validated against 10 rat tissues to ensure best representation of the gene and biologically relevant results. more...

Organism:

Rattus norvegicus

3 DataSets

21 Series

353 Samples

Download data