GSE113654[Accession] - GEO DataSets - NCBI

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Items: 5

Select item 2001136541.

Cyclic LSD1 recruitment and dynamic H3K4 methylation establish TRIM24-activated estrogen response

(Submitter supplied) The role of histone lysine methylation in estrogen receptor-alpha (ERα)-activated transcription is highly context-specific and poorly understood. Here, we show that lysine demethylase 1 (LSD1) mediates loss of H3 lysine 4 dimethylation (H3K4me2) in coordination with tripartite-motif-containing protein 24 (TRIM24)- regulated growth of breaset cancer-derived cells. We performed global profiling of histone H3K4me2 in comparison to genome-wide binding of TRIM24 in MCF7 cells when estrogen is depleted or added. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL21290
3 Samples

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Series

Accession:: GSE113654

ID:: 200113654

SRA Run Selector

Select item 1000212902.

Illumina HiSeq 3000 (Homo sapiens)

Organism:: Homo sapiens

1138 Series
28241 Samples

Platform

Accession:: GPL21290

ID:: 100021290

Select item 3031107293.

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL21290
Series:: GSE113654

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Sample

Accession:: GSM3110729

ID:: 303110729

SRA Run Selector

Select item 3031107284.

TRIM24 ChIP-seq in E2neg

Organism:: Homo sapiens

Source name:: MCF7 E2neg

Platform:: GPL21290
Series:: GSE113654

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Sample

Accession:: GSM3110728

ID:: 303110728

SRA Run Selector

Select item 3031107275.

TRIM24 ChIP-seq in E2pos

Organism:: Homo sapiens

Source name:: MCF7 E2pos

Platform:: GPL21290
Series:: GSE113654

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Sample

Accession:: GSM3110727

ID:: 303110727

SRA Run Selector

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