GEO DataSets

(Submitter supplied) Barrett Esophagus (BE) is a risk factor for the development of esophageal adenocarcinoma (EAC). As endemic obesity emerges as a risk factor for increasing numbers of EAC we utilized our IL-1b mouse model of BE to understand the impact of a high fat diet (HFD) on disease progression. Indeed, increased dysplasia development in HFD treated IL-1b mice correlated with an accelerated cytokine response with specific upregulation of IL-8 in esophageal tissue, which could be confirmed by specific overexpression of IL-8 in the BE mouse model. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL17400

9 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html MoGene-2_1-st-v1.na33.2.mm10.transcript.csv #%create_date=Thu Mar 28 17:33:46 2013 PDT #%chip_type=MoGene-2_1-st-v1 #%lib_set_name=MoGene-2_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm10 #%genome-version-ucsc=mm10 #%genome-version-ncbi=38 #%genome-version-create_date=2011-12-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm10 #%genome-lifted_from-version-ncbi=38 #%netaffx-annotation-date=2012-09-30 #%netaffx-annotation-netaffx-build=33 Protocol: see manufacturer's web site

Organism:

Mus musculus

214 Series

6 Related Platforms

3551 Samples

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