GEO DataSets

(Submitter supplied) The aim of this study was therefore to investigate molecular mechanisms associated with insulin sensitivity in skeletal muscle by relating global skeletal muscle gene expression with a surrogate measure of insulin sensitivity, i.e. homeostatic model assessment of insulin resistance (HOMA-IR). To identify genes with skeletal muscle expression related to insulin sensitivity, we obtained muscle biopsies from 38 non-diabetic participants in study A. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL7144 GPL4133

47 Samples

Download data: CEL, TXT

(Submitter supplied) To identify genes correlated to insulin sensitivity in skeletal muscle, we studied 38 non-diabetic men from Malmö, Sweden. Briefly, the Malmö Exercise Intervention cohort consists of sedentary but otherwise healthy male subjects from southern Sweden. They all have European ancestry and 18 of them have a first-degree family member with T2D. The mean age and body mass index (BMI) were 37.71 ± 0.71 years and 28.47 ± 0.48 kg/m2, respectively, and the mean 1/the homeostatic model assessment-insulin resistance (HOMA-IR) was 0.69 ± 0.04

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL7144

38 Samples

Download data: CEL

(Submitter supplied) Acute effects of different dietary fatty acids on the gene expression profiles of peripheral blood mononuclear cells in healthy young men. A randomized cross-over study. Gene expression profiles of peripheral blood mononuclear cells (PBMCs) have been used to reflect pathological and physiological states of humans. We theorized that these cells could also be used to show fatty acid specific gene expression profiles. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3704

Platform:

GPL7144

84 Samples

Download data: CEL

Analysis of peripheral blood mononuclear cells of individuals before and 6 hours after the consumption of shakes containing either mainly polyunsanturated (PUFA) or saturated fatty acids (SFA). Results provide insight into the molecular basis of the beneficial effect of PUFA on health.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 agent, 42 individual, 2 protocol sets

Platform:

GPL7144

Series:

GSE13466

84 Samples

Download data: CEL

(Submitter supplied) Fish oil supplementation is generally seen as beneficial for human health, due to the presence of n-3 polyunsaturated fatty acids (n-3 PUFAs). These fatty acids can elicit their effect through changes in gene expression. Effects of n-3 PUFAs on gene expression of inflammatory and atherogenic markers have been shown in several in vitro and animal studies. However, little evidence is available on human in vivo studies on n-3 PUFA related gene expression. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL7144

96 Samples

Download data: CEL

(Submitter supplied) CDF file was created by Microarray Lab at the Molecular and Behavioral Neuroscience Institute at the University of Michigan. Oligonucleotide probes on GeneChips were reorganized based on the latest genome and transcriptome information. In this particular case the Entrez Gene database (build: Sept 11, 2006) was used as source. For the CDF file based on Entrez Gene: A probe must hit only one genomic location; Probes that can be mapped to the same target sequence in the correct direction are grouped together in the same probe set; Each probe set must contain at least three oligonucleotide probes and probes in a set are ordered according to their location in the corresponding exon. more...

Organism:

Homo sapiens

1 DataSet

4 Series

1 Related Platform

218 Samples

Download data: CDF

(Submitter supplied) This array has been designed by NuGO and manufactured by Affymetrix. NuGO is a European Union-funded Network of Excellence, the full title of which is 'The European Nutrigenomics Organisation: linking genomics, nutrition and health research'. This array contains aproximately 24.000 probesets, relevant to nutrigenomics studies. More info: http://www.nugo.org http://blog.bigcat.unimaas.nl/~martijn/NuGO/index.html Protocol: See manufacturer's web site

Organism:

Homo sapiens

1 DataSet

11 Series

2 Related Platforms

276 Samples

Download data: CDF, ZIP