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Proteus mirabilis UreR Coordinates Cellular Functions required for Urease Activity

(Submitter supplied) Catheter-associated urinary tract infections (CAUTIs) account for over 30% of acute nosocomial infections in the U.S. and generate $340 million in healthcare costs annually. A major causative agent of CAUTIs is Proteus mirabilis, an understudied Gram-negative pathogen noted for its ability to form urinary stones via the activity of urease. Urease mutants cannot induce stones and are attenuated in a murine UTI model, indicating this enzyme is essential to P. more...
Organism:
Proteus mirabilis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33818
18 Samples
Download data: XLSX
Series
Accession:
GSE254779
ID:
200254779

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