GEO DataSets

(Submitter supplied) To reconstruct the ancestry of animal innate immunity, we have developed the choanoflagellate Monosiga brevicollis, one of the closest living relatives of animals, as a model for studying mechanisms underlying pathogen recognition and immune response. We found that M. brevicollis is killed by exposure to Pseudomonas aeruginosa bacteria and selectively avoids ingesting them. Moreover, M. brevicollis expresses STING, which, in animals, activates innate immune pathways in response to cyclic dinucleotides during pathogen sensing. more...

Organism:

Monosiga brevicollis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL30126 GPL30125

24 Samples

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