GPL29914[Accession] - GEO DataSets - NCBI

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Select item 2002426361.

Aberrant RNA polymerase Initiation and Processivity on the Genome of a Herpes Simplex Virus 1 Mutant Lacking ICP27

(Submitter supplied) Within the first 15 minutes of infection, herpes simplex virus 1 (HSV-1) immediate early proteins repurpose cellular RNA polymerase (Pol II) for viral transcription. An important role of the viral infected cell protein 27 (ICP27) is to facilitate viral pre-mRNA processing and export of viral mRNA to the cytoplasm. Here, we use precision nuclear run-on followed by deep sequencing (PRO-seq) to characterize transcription of a viral ICP27 null mutant. more...

Organism:: Human alphaherpesvirus 1; Drosophila melanogaster; Homo sapiens

Type:: Other

Platform:: GPL29914
12 Samples

Download data: BW

Series

Accession:: GSE242636

ID:: 200242636

PubMed Similar studies

Select item 2001695742.

ICP22 of Herpes Simplex Virus 1 decreases RNA Polymerase Processivity

(Submitter supplied) These data files consist of Illumina next seq 500 sequencing data from precision nuclear run-on and global nuclear run-on experiments conducted with human epithelial Hep2 cells that have been infected with human herpes simplex virus-1 (F) strain mutants. The results of these studies suggest that ICP22 is necessary for reducing Pol II processivity on the viral genome which results in its maintenance on the viral genome over the course of infection. more...

Organism:: Human alphaherpesvirus 1; Drosophila melanogaster; Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL29914
32 Samples

Download data: BW

Series

Accession:: GSE169574

ID:: 200169574

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000299143.

NextSeq 550 (Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1)

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

2 Series
44 Samples

Platform

Accession:: GPL29914

ID:: 100029914

Select item 3077663974.

Hep2 cells infected with d27LacZ (MOI 5) at 6 hpi synchronous infection replicate2

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766397

ID:: 307766397

SRA Run Selector

Select item 3077663965.

Hep2 cells infected with d27LacZ (MOI 5) at 6 hpi synchronous infection replicate 1

Organism:: Homo sapiens; Drosophila melanogaster; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766396

ID:: 307766396

SRA Run Selector

Select item 3077663956.

Hep2 cells infected with wt KOS (MOI 5) at 6 hpi synchronous infection replicate 2

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766395

ID:: 307766395

SRA Run Selector

Select item 3077663947.

Hep2 cells infected with wt KOS (MOI 5) at 6 hpi synchronous infection replicate 1

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766394

ID:: 307766394

SRA Run Selector

Select item 3077663938.

Hep2 cells infected with d27LacZ (MOI 5) at 3 hpi synchronous infection replicate 2

Organism:: Human alphaherpesvirus 1; Drosophila melanogaster; Homo sapiens

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766393

ID:: 307766393

SRA Run Selector

Select item 3077663929.

Hep2 cells infected wit h d27LacZ (MOI5) at 3 hpi synchronous infection replicate 1

Organism:: Human alphaherpesvirus 1; Drosophila melanogaster; Homo sapiens

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766392

ID:: 307766392

SRA Run Selector

Select item 30776639110.

Hep2 cells infected with wt KOS (MOI 5) at 3 hpi synchronous infection replicate 2

Organism:: Human alphaherpesvirus 1; Drosophila melanogaster; Homo sapiens

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766391

ID:: 307766391

SRA Run Selector

Select item 30776639011.

Hep2 cells infected with wt KOS (MOI 5) at 3 hpi synchronous infection replicate 1

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766390

ID:: 307766390

SRA Run Selector

Select item 30776638912.

Hep2 cells infected with d27LacZ (MOI 5) at 1.5 hpi synchronous infection replicate 2

Organism:: Homo sapiens; Drosophila melanogaster; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766389

ID:: 307766389

SRA Run Selector

Select item 30776638813.

Hep2 cells infected with d27LacZ (MOI 5) at 1.5 hpi synchronous infection replicate 1

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766388

ID:: 307766388

SRA Run Selector

Select item 30776638714.

Hep2 cells infected with wt KOS (MOI 5) at 1.5 hpi synchronous infection replicate 2

Organism:: Homo sapiens; Drosophila melanogaster; Human alphaherpesvirus 1

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766387

ID:: 307766387

SRA Run Selector

Select item 30776638615.

Hep2 cells infected with wt KOS (MOI 5) at 1.5 hpi synchronous infection replicate 1

Organism:: Homo sapiens; Human alphaherpesvirus 1; Drosophila melanogaster

Source name:: Human, Drosophila, and HSV-1 (KOS)

Platform:: GPL29914
Series:: GSE242636

Download data: BW

Sample

Accession:: GSM7766386

ID:: 307766386

SRA Run Selector

Select item 30572041416.

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: HeP-2 cells, S2 Cells, HSV-16

Platform:: GPL29914
Series:: GSE169574

Download data: BW

Sample

Accession:: GSM5720414

ID:: 305720414

SRA Run Selector

Select item 30572041317.

Organism:: Drosophila melanogaster; Homo sapiens; Human alphaherpesvirus 1

Source name:: HeP-2 cells, S2 Cells, HSV-15

Platform:: GPL29914
Series:: GSE169574

Download data: BW

Sample

Accession:: GSM5720413

ID:: 305720413

SRA Run Selector

Select item 30572041218.

Organism:: Homo sapiens; Human alphaherpesvirus 1; Drosophila melanogaster

Source name:: HeP-2 cells, S2 Cells, HSV-14

Platform:: GPL29914
Series:: GSE169574

Download data: BW

Sample

Accession:: GSM5720412

ID:: 305720412

SRA Run Selector

Select item 30572041119.

Organism:: Human alphaherpesvirus 1; Homo sapiens; Drosophila melanogaster

Source name:: HeP-2 cells, S2 Cells, HSV-13

Platform:: GPL29914
Series:: GSE169574

Download data: BW

Sample

Accession:: GSM5720411

ID:: 305720411

SRA Run Selector

Select item 30572041020.

Organism:: Human alphaherpesvirus 1; Homo sapiens; Drosophila melanogaster

Source name:: HeP-2 cells, S2 Cells, HSV-12

Platform:: GPL29914
Series:: GSE169574

Download data: BW

Sample

Accession:: GSM5720410

ID:: 305720410

SRA Run Selector

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