GEO DataSets

(Submitter supplied) The brain requires complex mechanisms of genome regulation to encode and store behavioural information. In mammals, DNA methylation deposited at non-CG dinucleotides characterises brain epigenomes. However, it is unclear to what extent this non-canonical form of DNA methylation is evolutionarily conserved. To test this we profile brain cytosine methylation across the major vertebrate lineages, amphioxus, honeybee and octopus, finding that non-CG methylation in adult brain methylomes is restricted to vertebrates. more...

Organism:

Apis mellifera; Callorhinchus milii; Octopus bimaculoides; Gallus gallus; Ornithorhynchus anatinus; Lethenteron camtschaticum; Branchiostoma lanceolatum; Danio rerio; Monodelphis domestica

Type:

Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

9 related Platforms

11 Samples

Download data: CGMAP, TSV