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Items: 2

1.

The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
4 related Platforms
246 Samples
Download data: RCC
Series
Accession:
GSE101689
ID:
200101689

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases I

(Submitter supplied) Microglia play a pivotal role in the maintenance of brain homeostasis, but lose their homeostatic function during the course of neurodegenerative disorders. We identified a specific APOE-dependent molecular signature in microglia isolated from mouse models of amyotrophic lateral sclerosis, multiple sclerosis and Alzheimer’s disease (SOD1, EAE and APP-PS1) and in microglia surrounding neuritic A-plaques in human Alzheimer’s disease brain. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL23811
63 Samples
Download data: RCC
Series
Accession:
GSE101686
ID:
200101686

PubMed Full text in PMC Similar studies Analyze with GEO2R

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db=gds|term=GPL23811[RGSE]|query=1|qty=2|blobid=MCID_6750d6078288966b3959c527|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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