GPL17946[RGSE] - GEO DataSets

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Items: 2

Select item 2000589131.

Transcriptome profiling of responses of mouse peritoneal macrophages to oxLDL

(Submitter supplied) The goal of this study was to profile transcriptional changes of mouse peritoneal macrophages during foam cell formation induced by the atherogenic lipoprotein, oxidized LDL (oxLDL)

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL17946
6 Samples

Download data: CEL

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Accession:: GSE58913

ID:: 200058913

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Select item 2000524822.

Transcriptome profiling of plaque macrophages during atherosclerosis regression

(Submitter supplied) We have carried out a systems biology investigation of regulators controlling arterial plaque macrophage transcriptional changes in response to lipid lowering, in the Reversa mouse model of plaque regression in which poly I:C injections induce recombination-mediated inactivation of Mttp in the liver and (when combined with a switch to chow diet) restore normal lipid levels in an Ldlr-/-Apob100/100 mouse (Lieu et al., 2003, Circulation, v.107(9), pp.1315-21). more...