GEO DataSets

(Submitter supplied) Alcohol is a major risk factor for hepatocellular carcinoma (HCC) although the mechanisms underlying the alcohol-related liver carcinogenesis are still poorly understood. Alcohol is known to increase hepatocarcinogenesis possibly by inducing aberrant DNA methylation through the reduced provision of methyl groups within the hepatic one-carbon metabolism. Whether the epigenetically-regulated pathways in alcohol-associated HCC can be reversible or modifiable by nutritional factors is unknown. more...

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL15160

16 Samples

Download data: PAIR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Genome binding/occupancy profiling by array

Platforms:

GPL15160 GPL18451

32 Samples

Download data: PAIR

(Submitter supplied) Malignant melanoma is the most fatal skin cancer with a high degree of genetic and epigenetic aberrations. To investigate the role of DNA methylation on melanoma heterogeneity, we performed methylated DNA immunoprecipitation (MeDIP) microarray analysis of 10 primary melanoma cell cultures.

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platforms:

GPL17148 GPL15160

10 Samples

Download data: PAIR, TXT

(Submitter supplied) Small cell lung cancer (SCLC) is a disease characterized by aggressive clinical behavior and lack of effective therapy. Due to its high tendency of early dissemination, only a third of patients have limited-stage disease at the time of diagnosis. SCLC is thought to derive from neuroendocrine cells of the lung. Although several molecular abnormalities in SCLC have been described, there are relatively few studies on epigenetic alterations in this type of tumor. more...

Organism:

Homo sapiens

Type:

Methylation profiling by genome tiling array

Platform:

GPL15160

29 Samples

Download data: GFF, PAIR

(Submitter supplied) Format: 3X720K Source: UCSC Build: HG18, NCBI 36 Probe Length: 50-75mer Median Probe Spacing: 104 090618_HG18_CpG_Refseq_Prom_MeDIP.ndf 090618_HG18_CpG_Refseq_Prom_MeDIP.pos 090618_HG18_CpG_Refseq_Prom_MeDIP.gff 090618_HG18_CpG_Refseq_Prom_MeDIP_HX3.ncd Protocol: see manufacturer's website

Organism:

Homo sapiens

4 Series

47 Samples

Download data: GFF, NCD, NDF, POS