GPL10743[RGSE] - GEO DataSets

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Items: 2

Select item 2000263891.

Losses of chromosome 5q and 14q mark a subset of gastric cancers with good clinical outcome

(Submitter supplied) Purpose: To improve clinical outcome of gastric cancer patients, most emphasis is on improving therapeutic regimens, including more extensive surgery as well as (neo)adjuvant chemotherapy. The present study set out to identify, based on DNA copy number profiling, subgroups of patients with different clinical outcomes who thus would qualify for different therapy intensities. Experimental Design: DNA of 206 gastric cancer patients was isolated and analyzed by genome wide array comparative genomic hybridization. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

4 related Platforms
183 Samples

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Accession:: GSE26389

ID:: 200026389

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Select item 2000234182.

Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers

(Submitter supplied) Purpose: Small bowel adenocarcinoma (SBA) is a rare cancer and consequently the number of clinical trials has been very limited due to the small numbers of patients. Chemotherapy regimens are currently rather arbitrarily chosen between either a colorectal (CRC) or a gastric cancer (GC) regimen. Chromosomal copy number aberrations are a hallmark of solid tumours and can be measured by array comparative genomic hybridization (aCGH). more...